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From iA wiki
See also: Getting Rid Of Spyware
SpyBot-Search & Destroy searches your hard drive for annoying and resource-wasting Spyware If SpyBot-S&D finds such modules, it can remove them. In most cases, the host still runs fine after removing the spyware/adware.
Another feature of Spybot Search & Destroy is the removal of usage tracks, which makes it more complicated for unknown spybots to transmit useful data. The list of last visited websites, opened files, started programs, cookies, all that and more can be cleaned. Supported are the three major browsers Internet Explorer, Netscape Communicator and Opera.
Spybot-Search & Destroy also contains some routines to find and correct invalid entries (regarding links left over from software uninstalled long ago, for example) into the registry (the global Windows database for settings).